Publications

We describe an electrochemical measurement technique that enables bioelectronic measurements of reporter proteins in living cells as an alternative to traditional optical fluorescence. Using electronically programmable microfluidics, the measurement is in turn used to control the concentration of an inducer input that regulates production of the protein from a genetic...

Microfabrication techniques were developed to create flexible 24 um thick glucose sensors on polyimide substrates. Measurements of the sensor performance, recorded as voltage potential, were carried out for a range of glucose concentrations (0 – 8 mM) in physiological saline (0.1 M NaCl, pH 7.4). The sensors show rapid response...

A new type of broadband link enabling extremely high-speed chip-to-chip communication is presented. The link is composed of fully integrated sub-mmWave on-chip traveling wave power couplers and a low-cost planar dielectric waveguide. This structure is based on a differentially driven half-mode substrate integrated waveguide supporting the first higher order hybrid...

Directly deposited optical-blocking filters (DD OBFs) have the potential to improve filter performance and lower risk and cost for future x-ray imaging spectroscopy missions. However, they have not been fully characterized on high-performance charge coupled devices (CCDs). This paper reports the results of DD OBFs processed on high-performance photon-counting CCDs...

Operation of a cw thulium laser emitting at 816 nm has been demonstrated in bulk Tm:YLF with 46% slope efficiency. Prior cw demonstrations of this transition have been limited to ZBLAN fiber hosts and prior lasing in bulk crystalline host material has been limited to quasi-cw operation due to population...

Electrically controlled micron-scale liquid lenses have been designed, fabricated and demonstrated, that provide both adjustable focusing and beam steering, with the goal of applying them to optogenetic in vivo mapping of brain activity with single cell resolution. The liquid lens is formed by the interface between two immiscible liquids which...

Canines remain the gold standard for explosives detection in many situations, and there is an ongoing desire for them to perform at the highest level. This goal requires canine training to be approached similarly to scientific sensor design. Developing a canine training regimen is made challenging by a lack of...

Microfluidic devices have the potential to automate and miniaturize biological experiments, but open-source sharing of device designs has lagged behind sharing of other resources such as software. Synthetic biologists have used microfluidics for DNA assembly, cell-free expression, and cell culture, but a combination of expense, device complexity, and reliance on...

We introduce a new type of actuator, the microhydraulic stepping actuator (MSA), which borrows design and operational concepts from biological muscle and stepper motors. MSAs offer a unique combination of power, efficiency, and scalability not easily achievable on the microscale. The actuator works by integrating surface tension forces produced by...

Laser strikes against aircraft are increasing at an alarming rate, driven by the availability of cheap powerful lasers and a lack of deterrence due to the challenges of locating and apprehending perpetrators. Although window coatings and pilot goggles effectively block laser light, uptake has been low due to high cost...