Many in-band full-duplex wireless systems transmit and receive on a single antenna to minimize redundancy and maintain compact form factors. For effective operation, all of these systems need to maximize transmit-to-receive isolation, which is limited by non-ideal antenna matching and non-zero circulator leakage. Several isolation-improvement techniques are investigated in this paper, and illustrate how RF components can be used to minimize the consequential self-interference of these systems. Two unique cancellation schemes were validated, and the isolation of a single-antenna transceiver was measured to improve by 15 and 33 dB over the 100 MHz bandwidth centered at 2.45 GHz.