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Integrative sensor networks, informatics, and modeling for precision and preventative medicine

Published in:
IEEE J. Biomed. Health, Vol. 24, No. 7, July 2020, pp. 1858-1859.

Summary

The topics of integrative sensor networks, informatics and modeling bring together the tightly coupled and rapidly developing fields of biomedical and health informatics and body sensor networks. Biomedical and health informatics encompasses methods to extract and communicate information from data in order to impact health, healthcare, life sciences and biomedicine. Body sensor networks provide one means to measure the needed data, through continuous monitoring in both clinical and free-living environments. Developments in these areas were highlighted at two co-located conferences: the 2019 IEEE-EMBS International Conferences on Biomedical and Health Informatics (BHI'19) and Wearable and Implantable Body Sensor Networks (BSN'19). BHI and BSN are long-standing IEEE EMBS conferences that provide a forum for researchers and leaders from academia, government and industry to share technical advances and new initiatives in these important areas. Through an open call for this special issue, eleven papers have been included for publication. The majority were presented in an initial form at the 2018 or 2019 BHI and BSN conferences. Nine of the papers were selected through a rigorous peer review. In addition, two keynote speakers from BHI'19 and BSN'19 have provided short position papers.
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Summary

The topics of integrative sensor networks, informatics and modeling bring together the tightly coupled and rapidly developing fields of biomedical and health informatics and body sensor networks. Biomedical and health informatics encompasses methods to extract and communicate information from data in order to impact health, healthcare, life sciences and biomedicine...

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Detecting intracranial hemorrhage with deep learning

Published in:
40th Int. Conf. of the IEEE Engineering in Medicine and Biology Society, EMBC, 17-21 July 2018.

Summary

Initial results are reported on automated detection of intracranial hemorrhage from CT, which would be valuable in a computer-aided diagnosis system to help the radiologist detect subtle hemorrhages. Previous work has taken a classic approach involving multiple steps of alignment, image processing, image corrections, handcrafted feature extraction, and classification. Our current work instead uses a deep convolutional neural network to simultaneously learn features and classification, eliminating the multiple hand-tuned steps. Performance is improved by computing the mean output for rotations of the input image. Postprocessing is additionally applied to the CNN output to significantly improve specificity. The database consists of 134 CT cases (4,300 images), divided into 60, 5, and 69 cases for training, validation, and test. Each case typically includes multiple hemorrhages. Performance on the test set was 81% sensitivity per lesion (34/42 lesions) and 98% specificity per case (45/46 cases). The sensitivity is comparable to previous results (on different datasets), but with a significantly higher specificity. In addition, insights are shared to improve performance as the database is expanded.
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Summary

Initial results are reported on automated detection of intracranial hemorrhage from CT, which would be valuable in a computer-aided diagnosis system to help the radiologist detect subtle hemorrhages. Previous work has taken a classic approach involving multiple steps of alignment, image processing, image corrections, handcrafted feature extraction, and classification. Our...

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Machine learning for medical ultrasound: status, methods, and future opportunities

Published in:
Abdom. Radiol., 2018, doi: 10.1007/s00261-018-1517-0.

Summary

Ultrasound (US) imaging is the most commonly performed cross-sectional diagnostic imaging modality in the practice of medicine. It is low-cost, non-ionizing, portable, and capable of real-time image acquisition and display. US is a rapidly evolving technology with significant challenges and opportunities. Challenges include high inter- and intra-operator variability and limited image quality control. Tremendous opportunities have arisen in the last decade as a result of exponential growth in available computational power coupled with progressive miniaturization of US devices. As US devices become smaller, enhanced computational capability can contribute significantly to decreasing variability through advanced image processing. In this paper, we review leading machine learning (ML) approaches and research directions in US, with an emphasis on recent ML advances. We also present our outlook on future opportunities for ML techniques to further improve clinical workflow and US-based disease diagnosis and characterization.
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Summary

Ultrasound (US) imaging is the most commonly performed cross-sectional diagnostic imaging modality in the practice of medicine. It is low-cost, non-ionizing, portable, and capable of real-time image acquisition and display. US is a rapidly evolving technology with significant challenges and opportunities. Challenges include high inter- and intra-operator variability and limited...

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Building low-power trustworthy systems: cyber-security considerations for real-time physiological status monitoring

Summary

Real-time monitoring of physiological data can reduce the likelihood of injury in noncombat military personnel and first-responders. MIT Lincoln Laboratory is developing a tactical Real-Time Physiological Status Monitoring (RT-PSM) system architecture and reference implementation named OBAN (Open Body Area Network), the purpose of which is to provide an open, government-owned framework for integrating multiple wearable sensors and applications. The OBAN implementation accepts data from various sensors enabling calculation of physiological strain information which may be used by squad leaders or medics to assess the team's health and enhance safety and effectiveness of mission execution. Security in terms of measurement integrity, confidentiality, and authenticity is an area of interest because OBAN system components exchange sensitive data in contested environments. In this paper, we analyze potential cyber-security threats and their associated risks to a generalized version of the OBAN architecture and identify directions for future research. The threat analysis is intended to inform the development of secure RT-PSM architectures and implementations.
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Summary

Real-time monitoring of physiological data can reduce the likelihood of injury in noncombat military personnel and first-responders. MIT Lincoln Laboratory is developing a tactical Real-Time Physiological Status Monitoring (RT-PSM) system architecture and reference implementation named OBAN (Open Body Area Network), the purpose of which is to provide an open, government-owned...

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